alpha-1 PDX Proteins

alpha-1 PDX Human recombinant proteins are validated for use in the following applications: Inhibition Assays. Available Product Grades: RUO. Gibco and Invitrogen proteins are some of the most frequently published proteins. alpha-1 PDX Protein have been referenced in 4 publications which can... alpha-1 PDX Human recombinant proteins are validated for use in the following applications: Inhibition Assays. Available Product Grades: RUO. Gibco and Invitrogen proteins are some of the most frequently published proteins. alpha-1 PDX Protein have been referenced in 4 publications which can be found in our reference library. Browse 1... alpha-1 PDX Human recombinant proteins are validated for use in the following applications: Inhibition Assays. Available Product Grades: RUO. Gibco and Invitrogen proteins are some of the most frequently published proteins. alpha-1 PDX Protein have been referenced in 4 publications which can be found in our reference library. Browse 1 protein, including biologically active options. Not finding the exact protein, grade or size needed? Contact us to discuss your specific application and product needs.... alpha-1 PDX Human recombinant proteins are validated for use in the following applications: Inhibition Assays. Available Product Grades: RUO. Gibco and Invitrogen proteins are some of the most frequently published proteins. alpha-1 PDX Protein have been referenced in 4 publications which can be found in our reference library. Browse 1 protein, including biologically active options. Not finding the exact protein, grade or size needed? Contact us to discuss your specific application and product needs.

Protein Information

Alpha1-PDX is a potent and selective inhibitor of furin (Ki = 0.6 nM). Alpha1-PDX was engineered by the construction of a variant of alpha1-antitrypsin that contains a minimal furin consensus sequence, RXXR. Cellular expression of alpha1-PDX effectively blocks the furin-dependent processing of protein precursors. In addition, extracellular application of alpha1-PDX can also block the processing of furin substrates. Alpha1-PDX has been shown to inhibit the processing of biologically significant proteins including many viral envelope glycoproteins, bacterial toxins, receptors and growth factors.

Synonyms

alpha1 PDX; Pyruvate Dehydrogenase Complex Component-X

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Invitrogen

Human alpha-1 PDX Recombinant Protein

Invitrogen

Human alpha-1 PDX Recombinant Protein

Species

Human

Expression System

E. coli

Product Grade

Research Use Only

Application

Ctrl IA

Price

Cat # RP-070

2.5 mg

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alpha-1 PDX Proteins

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